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The RRC Mass Spectrometry lab recently purchased a refurbished ABI 4700 MALDI TOF/TOF mass spectrometer. This instrument is located in the RRC East Mass Spectrometry Laboratory in Room 109A, Science and Engineering South Building, 845 West Taylor Street. The 4700 provides MS and MS/MS capability in a non-chromatographic setting and has both high and low energy fragmentation modes. This instrument is useful for protein and peptide sequencing experiments as well as small molecule studies. |
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Agilent 6410 Triple quadrupole tandem MS which is equipped with both a High Pressure HPLC system for high flow high-throughput analyses of small molecules and an Agilent Nanopump/ChipCube system that allows the 6410 to be used for targeted MRM analysis of proteomics samples using Agilent’s integrated nanochip-column-nanospray technology. Targeted MRM analysis allows investigators to detect and quantitate peptides with high sensitivity and specificity. This makes the system ideal for biomarker studies. |
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The LTQ-FT is a state of the art high resolution/high mass accuracy mass spectrometer ideally suited for proteomics studies using either top down or bottom up techniques. It is a tandem mass spectrometer with two dimensional nanoflow HPLC, nanospray and standard electrospray sources. It is located in Pharmacy Room 552. |
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ABI Voyager DE Pro MALDI-TOF |
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The Voyager DE Pro is a Time of Flight (TOF) mass spectrometer used for rapid determination of molecular weights of peptides and proteins and for peptide sequencing.
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The LTQ is a state of the art linear ion trap mass spectrometer equipped with a two dimensional HPLC system. This instrument can be used for tandem mass spectrometry based protein identification or quantitation. It is located in Pharmacy Room 552. |
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Instruments
